Deflazacort is a synthetic Glucocorticoid and is used to suppress inflammation. It has been proven to having a lower risk of side effects such as bone loss, glucose intolerance or Cushing’s syndrome than other available steroids.
Glucocorticoid (GC) are widely used for the suppression of inflammation in chronic inflammatory diseases such as asthma, R.A., inflammatory bowel disease and autoimmune diseases, all with increased expression of inflammatory genes.
GC bind to GR in the cytoplasm which then translocate to the nucleus, where they bind to GC response elements (GRE) on GC-responsive genes, resulting in increased transcription for genes coding for anti-inflammatory proteins
GC increases the synthesis of lipocortin-1 that has inhibitory effect on phospholipase A2 and therefore inhibits the production of inflammatory mediators as well as inhibit genes coding for COX-2.


Each Film coated tablet contains
Deflazacort……….. 6 mg


Hereditary problems of galactose intolerance
Cardiac disease
Gastritis or Esophagitis, ulcerative colitis if there is probability of impending perforation, active or latent peptic ulcer
Diabetes mellitus or a family history,